0000950123-11-089982.txt : 20111014 0000950123-11-089982.hdr.sgml : 20111014 20111014134047 ACCESSION NUMBER: 0000950123-11-089982 CONFORMED SUBMISSION TYPE: SC 13D/A PUBLIC DOCUMENT COUNT: 2 FILED AS OF DATE: 20111014 DATE AS OF CHANGE: 20111014 GROUP MEMBERS: ANSBERT GADICKE GROUP MEMBERS: DENNIS HENNER GROUP MEMBERS: KURT WHEELER GROUP MEMBERS: LUKE EVNIN GROUP MEMBERS: MICHAEL STEINMETZ GROUP MEMBERS: MPM ASSET MANAGEMENT INVESTORS 2003 BVIII LLC GROUP MEMBERS: MPM ASSET MANAGEMENT LLC GROUP MEMBERS: MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG GROUP MEMBERS: MPM BIOVENTURES III GP, L.P. GROUP MEMBERS: MPM BIOVENTURES III LLC GROUP MEMBERS: MPM BIOVENTURES III PARALLEL FUND, L.P. GROUP MEMBERS: MPM BIOVENTURES III, L.P. GROUP MEMBERS: MPM BIOVENTURES III-QP, L.P. GROUP MEMBERS: NICHOLAS GALAKATOS GROUP MEMBERS: NICHOLAS SIMON III SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: Zalicus Inc. CENTRAL INDEX KEY: 0001135906 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 043514457 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-81444 FILM NUMBER: 111141444 BUSINESS ADDRESS: STREET 1: 245 FIRST STREET STREET 2: 3RD FLOOR CITY: CAMBRIDGE STATE: MA ZIP: 02142 BUSINESS PHONE: 617-301-7000 MAIL ADDRESS: STREET 1: 245 FIRST STREET STREET 2: 3RD FLOOR CITY: CAMBRIDGE STATE: MA ZIP: 02142 FORMER COMPANY: FORMER CONFORMED NAME: COMBINATORX, INC DATE OF NAME CHANGE: 20041208 FORMER COMPANY: FORMER CONFORMED NAME: COMBINATORX INC DATE OF NAME CHANGE: 20010301 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: MPM BIOVENTURES III-QP L.P. CENTRAL INDEX KEY: 0001173409 IRS NUMBER: 000000000 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A BUSINESS ADDRESS: STREET 1: C/O MPM ASSET MANAGEMENT STREET 2: 200 CLARENDON ST., 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 BUSINESS PHONE: 617 425 9200 MAIL ADDRESS: STREET 1: C/O MPM ASSET MANAGEMENT STREET 2: 200 CLARENDON ST., 54TH FLOOR CITY: BOSTON STATE: MA ZIP: 02116 FORMER COMPANY: FORMER CONFORMED NAME: MPM BIOVENTURES III QP LP DATE OF NAME CHANGE: 20031124 FORMER COMPANY: FORMER CONFORMED NAME: MPM BIO VENTURES III QP LP DATE OF NAME CHANGE: 20020514 SC 13D/A 1 c23327sc13dza.htm SCHEDULE 13D/A Schedule 13D/A
 
 
UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
SCHEDULE 13D
Under the Securities Exchange Act of 1934
(Amendment No. 2)*
ZALICUS, INC.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
98887C 105
(CUSIP Number)
LUKE EVNIN
MPM ASSET MANAGEMENT
THE JOHN HANCOCK TOWER
200 CLARENDON STREET, 54TH FLOOR
BOSTON, MASSACHUSETTS 02116
TELEPHONE: (617) 425-9200
(Name, Address and Telephone Number of Person
Authorized to Receive Notices and Communications)
October 7, 2011
(Date of Event Which Requires Filing of this Statement)
If the filing person has previously filed a statement on Schedule 13G to report the acquisition that is the subject of this Schedule 13D, and is filing this schedule because of §§240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check the following box. o
Note: Schedules filed in paper format shall include a signed original and five copies of the schedule, including all exhibits. See §240.13d-7 for other parties to whom copies are to be sent.
     
*  
The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page.
The information required on the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).
 
 

 

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM BioVentures III-QP, L.P.
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   11,048,038
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   11,048,038
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  11,048,038
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  11.1%(2)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  PN
(1) This Schedule is filed by MPM BioVentures III-QP, L.P. (“BV III QP”), MPM BioVentures III, L.P. (“BV III”), MPM BioVentures III Parallel Fund, L.P. (“BV III PF”), MPM BioVentures III GmbH & Co. Beteiligungs KG (“BV III KG”), MPM Asset Management Investors 2003 BVIII LLC (“AM LLC”), MPM Asset Management LLC (“MPM AM”), MPM BioVentures III GP, L.P. (“BV III GP”) and MPM BioVentures III LLC (“BV III LLC” and collectively with BV III QP, BV III, BV III PF, BV III KG, AM LLC and BV III GP, the “MPM Entities”) and Luke Evnin, Ansbert Gadicke, Nicholas Galakatos, Michael Steinmetz, Kurt Wheeler, Nicholas Simon III and Dennis Henner (collectively, the “Listed Persons”). BVIII GP and BVIII LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Listed Persons are Series A members of BV III LLC and managers of AM LLC. Luke Evnin and Ansbert Gadicke are members of MPM AM. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) This percentage is calculated based upon 99,237,510 shares of Zalicus, Inc.’s (the “Issuer’s”) common stock, par value $0.001 per share (the “Common Stock”) outstanding on August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM BioVentures III, L.P.
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   741,675
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   741,675
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  741,675
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  0.8%(2)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  PN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM Asset Management Investors 2003 BVIII LLC
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   213,605
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   213,605
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  213,605
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  0.2%(2)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  00
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM BioVentures III Parallel Fund, L.P.
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   332,668
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   332,668
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  332,668
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  0.3%(2)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  PN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM BioVentures III GmbH & Co. Beteiligungs KG
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Germany
       
  7   SOLE VOTING POWER
     
NUMBER OF   932,451
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   932,451
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  932,451
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  0.9%(2)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  PN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM Asset Management LLC
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   70,092
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   0
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   70,092
       
WITH 10   SHARED DISPOSITIVE POWER
     
    0
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  70,092
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  0.1%(2)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  OO
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM BioVentures III GP, L.P.
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1)
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,054,832(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,054,832(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,054,832(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.2%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  PN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; and 932,451 shares of Common Stock held by BV III KG. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

MPM BioVentures III LLC
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  WC
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  Delaware
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,054,832(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,054,832(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,054,832(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.2%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  OO
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; and 932,451 shares of Common Stock held by BV III KG. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Luke Evnin
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,338,529(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,338,529(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,338,529(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; 213,605 shares of Common Stock held by AM LLC; and 70,092 shares of Common Stock held by MPM AM. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC, a manager of AM LLC and a member of MPM AM.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Ansbert Gadicke
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,338,529(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,338,529(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,338,529(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; 213,605 shares of Common Stock held by AM LLC; and 70,092 shares of Common Stock held by MPM AM. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC, a manager of AM LLC and a member of MPM AM.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Nicholas Galakatos
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,268,437(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,268,437(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,268,437(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; and 213,605 shares of Common Stock held by AM LLC. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC and a manager of AM LLC.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Michael Steinmetz
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,268,437(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,268,437(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,268,437(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; and 213,605 shares of Common Stock held by AM LLC. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC and a manager of AM LLC.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Kurt Wheeler
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,268,437(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,268,437(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,268,437(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; and 213,605 shares of Common Stock held by AM LLC. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC and a manager of AM LLC.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
20010A103 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Nicholas Simon III
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,268,437(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,268,437(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,268,437(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; and 213,605 shares of Common Stock held by AM LLC. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC and a manager of AM LLC.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

                     
CUSIP No.
  
98887C 105 
 13D

 

           
1   NAMES OF REPORTING PERSONS

Dennis Henner
     
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
  (a)   o 
  (b)   þ(1) 
     
3   SEC USE ONLY
   
   
     
4   SOURCE OF FUNDS (SEE INSTRUCTIONS)
   
  OO
     
5   CHECK IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) OR 2(e)
   
  o
     
6   CITIZENSHIP OR PLACE OF ORGANIZATION
   
  United States
       
  7   SOLE VOTING POWER
     
NUMBER OF   0
       
SHARES 8   SHARED VOTING POWER
BENEFICIALLY    
OWNED BY   13,268,437(2)
       
EACH 9   SOLE DISPOSITIVE POWER
REPORTING    
PERSON   0
       
WITH 10   SHARED DISPOSITIVE POWER
     
    13,268,437(2)
     
11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
   
  13,268,437(2)
     
12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS)
   
  o
     
13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)
   
  13.4%(3)
     
14   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS)
   
  IN
(1) This Schedule is filed by the MPM Entities and the Listed Persons. The MPM Entities and the Listed Persons expressly disclaim status as a “group” for purposes of this Schedule 13D.
(2) Consists of 11,048,038 shares of Common Stock held by BV III QP; 741,675 shares of Common Stock held by BV III; 332,668 shares of Common Stock held by BV III PF; 932,451 shares of Common Stock held by BV III KG; and 213,605 shares of Common Stock held by AM LLC. BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The Reporting Person is a Series A member of BV III LLC and a manager of AM LLC.
(3) This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.

 

Explanatory Note:
This Amendment No. 2 to Schedule 13D (this “Schedule 13D”) amends and supplements the Schedule 13D previously filed by the undersigned with the Securities and Exchange Commission on January 5, 2010 and amended by Amendment No. 1 dated March 17, 2010 (as amended, the “Original Schedule 13D”). This Schedule 13D/A is being filed to report the open market sales of shares of common stock of Zalicus, Inc. (the “Company”) by the MPM Entities.
All capitalized terms not otherwise defined herein shall have the meaning ascribed to the terms in the Original Schedule 13D. The Original Schedule 13D is hereby further amended and supplemented as follows and, except as expressly amended below, the Original Schedule 13D remains in full force and effect.
Item 4. Purpose of Transaction
Item 4 of the Original Schedule 13D is hereby amended and supplemented by adding the following paragraph at the end of Item 4:
The MPM Entities sold an aggregate of 1,295,432 shares of Common Stock in open market transactions from September 26, 2011 through October 10, 2011 for aggregate proceeds of $1,336,833.30.
Item 5. Interest in Securities of the Issuer
“Item 5 of the Original Schedule 13D is hereby amended and restated in its entirety as follows:
(a) — (b) The following information with respect to the ownership of the common stock of the Issuer by the Reporting Persons is provided as of October 10, 2011:
                                                         
                    Shared     Sole     Shared              
    Shares Held     Sole Voting     Voting     Dispositive     Dispositive     Beneficial     Percentage of  
Filing Person   Directly     Power     Power     Power     Power     Ownership     Class (1)  
BV III QP
     11,048,038       11,048,038       0       11,048,038       0       11,048,038       11.1 %
 
                                                        
BV III
     741,675       741,675       0       741,675       0       741,675       0.8 %
 
                                                        
BV III PF
     332,668       332,668       0       332,668       0       332,668       0.3 %
BV III KG
     932,451       932,451       0       932,451       0       932,451       0.9 %
AM LLC
     213,605       213,605       0       213,605       0       213,605       0.2 %
MPM AM
     70,092       70,092       0       70,092       0       70,092       0.1 %
 
                                                        
BV III GP(2)
     0       0       13,054,832       0       13,054,832       13,054,832       13.2 %
 
                                                        
BV III LLC(2)
     0       0       13,054,832       0       13,054,832       13,054,832       13.2 %
Luke Evnin(3)(4)
     0       0       13,338,529       0       13,338,529       13,338,529       13.4 %
Ansbert Gadicke(3)(4)
     0       0       13,338,529       0       13,338,529       13,338,529       13.4 %
Nicholas Galakatos(3)
     0       0       13,268,437       0       13,268,437       13,268,437       13.4 %
Michael Steinmetz(3)
     0       0       13,268,437       0       13,268,437       13,268,437       13.4 %
Kurt Wheeler(3)
     0       0       13,268,437       0       13,268,437       13,268,437       13.4 %
Nicholas Simon III(3)
     0       0       13,268,437       0       13,268,437       13,268,437       13.4 %
Dennis Henner(3)
     0       0       13,268,437       0       13,268,437       13,268,437       13.4 %
     
(1)  
This percentage is calculated based upon 99,237,510 shares of Issuer’s Common Stock outstanding as of August 3, 2011, as disclosed in the Issuer’s Quarterly Report on Form 10-Q, filed with the Securities and Exchange Commission on August 4, 2011.
 
(2)  
BV III GP and BV III LLC are the direct and indirect general partners of BV III QP, BV III, BV III PF and BV III KG. The securities with respect to which these entities share voting and dispositive power are held as follows: 11,048,038 shares of Common Stock by BV III QP; 741,675 shares of Common Stock by BV III; 332,605 shares of Common Stock by BV III PF; and 932,451 shares of Common Stock by BV III KG.
 

 

 

 

     
(3)  
These Filing Persons are Series A Members of BV III LLC and managers of AM LLC. The securities with respect to which these Filing Persons share voting and dispositive power are held as follows: 11,048,038 shares of Common Stock by BV III QP; 741,675 shares of Common Stock by BV III; 332,668 shares of Common Stock by BV III PF; 932,451 shares of Common Stock by BV III KG; and 213,605 shares of Common Stock by AM LLC.
 
(4)  
Also includes 70,092 shares of Common Stock held by MPM AM, of which these Filing Persons are members and with respect to which these Filing Persons share voting and dispositive power.
(c) The Reporting Persons sold the following shares of Common Stock in the open market:
                     
MPM Entity   Date of Transaction   Number of Shares Sold     Price Per Share  
BV III QP
   September 26, 2011     174,808     $ 1.11 (1)
BV III
   September 26, 2011     11,754     $ 1.11 (1)
BV III PF
   September 26, 2011     5,279     $ 1.11 (1)
BV III KG
   September 26, 2011     14,774     $ 1.11 (1)
AM LLC
   September 26, 2011     3,385     $ 1.11 (1)
BV III QP
   September 27, 2011     166,485     $ 1.09 (2)
BV III
   September 27, 2011     11,194     $ 1.09 (2)
BV III PF
   September 27, 2011     5,028     $ 1.09 (2)
BV III KG
   September 27, 2011     14,070     $ 1.09 (2)
AM LLC
   September 27, 2011     3,223     $ 1.09 (2)
BV III QP
   September 28, 2011     83,242     $ 1.02 (3)
BV III
   September 28, 2011     5,597     $ 1.02 (3)
BV III PF
   September 28, 2011     2,514     $ 1.02 (3)
BV III KG
   September 28, 2011     7,035     $ 1.02 (3)
AM LLC
   September 28, 2011     1,612     $ 1.02 (3)
BV III QP
   September 29, 2011     42,782     $ 1.02  
BV III
   September 29, 2011     2,876     $ 1.02  
BV III PF
   September 29, 2011     1,292     $ 1.02  
BV III KG
   September 29, 2011     3,615     $ 1.02  
AM LLC
   September 29, 2011     828     $ 1.02  
MPM AM
   September 29, 2011     2,407     $ 1.02  
BV III QP
   September 30, 2011     19,300     $ 1.02  
BV III
   September 30, 2011     1,298     $ 1.02  
BV III PF
   September 30, 2011     583     $ 1.02  
BV III KG
   September 30, 2011     1,631     $ 1.02  
AM LLC
   September 30, 2011     374     $ 1.02  
MPM AM
   September 30, 2011     122     $ 1.02  
BV III QP
   October, 5, 2011     27,430     $ 1.02  
BV III
   October, 5, 2011     1,844     $ 1.02  
BV III PF
   October, 5, 2011     828     $ 1.02  
BV III KG
   October, 5, 2011     2,318     $ 1.02  
AM LLC
   October, 5, 2011     531     $ 1.02  
MPM AM
   October, 5, 2011     173     $ 1.02  
BV III QP
   October 6, 2011     140,773     $ 1.02 (3)
BV III
   October 6, 2011     9,465     $ 1.02 (3)

 

 

 

                     
MPM Entity   Date of Transaction   Number of Shares Sold     Price Per Share  
BV III PF
   October 6, 2011     4,252     $ 1.02 (3)
BV III KG
   October 6, 2011     11,897     $ 1.02 (3)
AM LLC
   October 6, 2011     2,726     $ 1.02 (3)
MPM AM
   October 6, 2011     887     $ 1.02 (3)
BV III QP
   October 7, 2011     227,889     $ 1.03 (4)
BV III
   October 7, 2011     15,323     $ 1.03 (4)
BV III PF
   October 7, 2011     6,882     $ 1.03 (4)
BV III KG
   October 7, 2011     19,259     $ 1.03 (4)
AM LLC
   October 7, 2011     4,412     $ 1.03 (4)
MPM AM
   October 7, 2011     1,435     $ 1.03 (4)
BV III QP
   October 10, 2011     190,459     $ 1.03 (4)
BV III
   October 10, 2011     12,806     $ 1.03 (4)
BV III PF
   October 10, 2011     5,752     $ 1.03 (4)
BV III KG
   October 10, 2011     16,096     $ 1.03 (4)
AM LLC
   October 10, 2011     3,688     $ 1.03 (4)
MPM AM
   October 10, 2011     1,199     $ 1.03 (4)
     
(1)  
Represents the weighted average sales price for the price increments ranging from $1.07 to $1.16.
 
(2)  
Represents the weighted average sales price for the price increments ranging from $1.01 to $1.13.
 
(3)  
Represents the weighted average sales price for the price increments ranging from $1.02 to $1.03.
 
(4)  
Represents the weighted average sales price for the price increments ranging from $1.02 to $1.06.
(d) Not applicable.
(e) Not applicable.
The information provided and incorporated by reference in Item 3 and Item 6 is hereby incorporated by reference in this Item 5.
Item 7. Material to Be Filed as Exhibits
Item 7 of the Original Schedule 13D is hereby supplemented by adding the following in appropriate order:
D. Agreement regarding filing of joint Schedule 13D/A.

 

 

 

SIGNATURES
After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Date: October 13, 2011
                     
MPM BIOVENTURES III, L.P.       MPM BIOVENTURES III-QP, L.P.    
 
                    
By:
  MPM BioVentures III GP, L.P.,
its General Partner 		      By:   MPM BioVentures III GP, L.P.,
its General Partner		    
 
                    
By:
  MPM BioVentures III LLC,
its General Partner 		      By:   MPM BioVentures III LLC,
its General Partner		    
 
                    
By:
     /s/ Luke Evnin       By:   /s/ Luke Evnin    
 
 
 
Name: Luke Evnin 		         
 
Name: Luke Evnin 		   
 
  Title: Series A Member           Title: Series A Member    
 
                    
MPM BIOVENTURES III PARALLEL FUND, L.P.       MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG    
 
                    
By:
  MPM BioVentures III GP, L.P.,
its General Partner 		      By:   MPM BioVentures III GP, L.P.,
in its capacity as the Managing Limited Partner		    
 
                    
By:
  MPM BioVentures III LLC,
its General Partner 		      By:   MPM BioVentures III LLC,
its General Partner		    
 
                    
By:
     /s/ Luke Evnin                
 
                   
 
  Name: Luke Evnin       By:      /s/ Luke Evnin
 
    
 
  Title: Series A Member           Name: Luke Evnin    
 
              Title: Series A Member    
 
                    
MPM ASSET MANAGEMENT INVESTORS 2003
BVIII LLC		       MPM BIOVENTURES III GP, L.P.    
 
          By:   MPM BioVentures III LLC,
its General Partner		    
 
                    
By:
     /s/ Luke Evnin
 
Name: Luke Evnin 		               
 
  Title: Manager       By:      /s/ Luke Evnin
 
Name: Luke Evnin 		   
 
              Title: Series A Member    
 
                    
MPM BIOVENTURES III LLC       MPM ASSET MANAGEMENT LLC    
 
                    
By:
     /s/ Luke Evnin
 
Name: Luke Evnin 		      By:      /s/ Luke Evnin
 
Name: Luke Evnin 		   
 
  Title: Series A Member           Title: Member    
 
                    
 
     /s/ Luke Evnin              /s/ Ansbert Gadicke    
             
 
  Luke Evnin           Ansbert Gadicke    
 
                    
 
     /s/ Nicholas Galakatos              /s/ Michael Steinmetz    
             
 
  Nicholas Galakatos           Michael Steinmetz    

 

 

 

                     
 
     /s/ Kurt Wheeler              /s/ Nicholas Simon III    
             
 
  Kurt Wheeler           Nicholas Simon III    
 
                    
 
     /s/ Dennis Henner                
                 
 
  Dennis Henner                
The original statement shall be signed by each person on whose behalf the statement is filed or his authorized representative. If the statement is signed on behalf of a person by his authorized representative (other than an executive officer or general partner of the filing person), evidence of the representative’s authority to sign on behalf of such person shall be filed with the statement: provided, however, that a power of attorney for this purpose which is already on file with the Commission may be incorporated by reference. The name and any title of each person who signs the statement shall be typed or printed beneath his signature.
Attention: Intentional misstatements or omissions of fact
constitute Federal criminal violations (See 18 U.S.C. 1001)

 

 

 

EXHIBIT INDEX
D. Agreement regarding filing of joint Schedule 13D/A.

 

 

EX-99.4 2 c23327exv99w4.htm EXHIBIT D Exhibit D
Exhibit D
JOINT FILING STATEMENT
I, the undersigned, hereby express my agreement that the attached Schedule 13D/A (and any amendments thereto) relating to the Common Stock of Zalicus, Inc. is filed on behalf of each of the undersigned.
Dated: October 13, 2011
                     
MPM BIOVENTURES III, L.P.       MPM BIOVENTURES III-QP, L.P.    
 
                    
By:
  MPM BioVentures III GP, L.P.,
its General Partner 		      By:   MPM BioVentures III GP, L.P.,
its General Partner		    
 
                    
By:
  MPM BioVentures III LLC,
its General Partner 		      By:   MPM BioVentures III LLC,
its General Partner		    
 
                    
By:
     /s/ Luke Evnin
 
Name: Luke Evnin 		      By:      /s/ Luke Evnin
 
Name: Luke Evnin 		   
 
  Title: Series A Member           Title: Series A Member    
 
                    
MPM BIOVENTURES III PARALLEL FUND, L.P.       MPM BIOVENTURES III GMBH & CO. BETEILIGUNGS KG    
 
                    
By:
  MPM BioVentures III GP, L.P., its General Partner       By:   MPM BioVentures III GP, L.P., in its capacity as the Managing Limited Partner    
 
                    
By:
  MPM BioVentures III LLC,
its General Partner 		      By:   MPM BioVentures III LLC,
its General Partner		    
 
                    
By:
     /s/ Luke Evnin
 
                
 
  Name: Luke Evnin       By:      /s/ Luke Evnin
 
    
 
  Title: Series A Member           Name: Luke Evnin    
 
              Title: Series A Member    
 
                    
MPM ASSET MANAGEMENT INVESTORS 2003
BVIII LLC		       MPM BIOVENTURES III GP, L.P.    
 
          By:   MPM BioVentures III LLC,
its General Partner		    
 
                    
By:
     /s/ Luke Evnin
 
Name: Luke Evnin 		               
 
  Title: Manager       By:      /s/ Luke Evnin
 
Name: Luke Evnin 		   
 
              Title: Series A Member    
 
                    
MPM BIOVENTURES III LLC       MPM ASSET MANAGEMENT LLC    
 
                    
By:
     /s/ Luke Evnin
 
Name: Luke Evnin 		      By:      /s/ Luke Evnin
 
Name: Luke Evnin 		   
 
  Title: Series A Member           Title: Member    
 
                    
 
     /s/ Luke Evnin              /s/ Ansbert Gadicke    
             
 
  Luke Evnin           Ansbert Gadicke    
 
                    
 
     /s/ Nicholas Galakatos              /s/ Michael Steinmetz    
             
 
  Nicholas Galakatos           Michael Steinmetz    

 

 

 

                     
 
  /s / Kurt Wheeler              /s/ Nicholas Simon III    
             
 
  Kurt Wheeler           Nicholas Simon III    
 
                    
 
     /s/ Dennis Henner                
                 
 
  Dennis Henner